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公司介绍
位于生技圣地--美国圣地亚哥的Abbiotec,是2007年新成立的一间生物技术公司,其产品在生命科学实验有着广泛的应用;Abbiotec公司专注于开发抗体,多肽,蛋白等试剂和使其不断市场化;Abbiotec的专有技术使其能够高效的挑选,设计和生产抗体,裂解物,以及各种试剂,让研究人员能够更专注于他们的研究。高质量、创新与完整的产品、合理的价格为Abbiotec不变的坚持与承诺;Abbiotec将不断为满足客户的需要和让他们获得最好的成果而努力。|产品系列:Antibodies、Peptides...

Abbiotec/KAI1 Antibody/253705/0.1 mg

  • 产品编号: 253705
  • 美  元  价: $341.00
  • 会  员  价: 待定
  • 品       牌: Abbiotec
  • 产       地: 美国
  • 公       司: Abbiotec, LLC.
  • 产品分类: ref="." class="index">首页 > Abbiotec/KAI1 Antibody/253705/0.1 mg
  • 公司分类: antibodies
:0.1 mg
Cat. No.:253705
Unit:0.1 mg
Isotype:Rabbit Ig
Applications:E
Species Reactivity:H
Format:Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Alternate Names:KAI1 ; CD82 antigen; tetraspanin-27; Tspan-27; suppressor of tumorgenicity-6
Accession No. :NP_002222
Antigen:KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human KAI1.
Application Notes:E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:50-1:200
Storage:Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Abbiotec/KAI1 Antibody/253705/0.1 mg
  • Abbiotec/KAI1 Antibody/253705/0.1 mg
  • Abbiotec/KAI1 Antibody/253705/0.1 mg
商品介绍
KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.
品牌介绍

位于生技圣地--美国圣地亚哥的Abbiotec,是2007年新成立的一间生物技术公司,其产品在生命科学实验有着广泛的应用;Abbiotec公司专注于开发抗体,多肽,蛋白等试剂和使其不断市场化;Abbiotec的专有技术使其能够高效的挑选,设计和生产抗体,裂解物,以及各种试剂,让研究人员能够更专注于他们的研究。高质量、创新与完整的产品、合理的价格为Abbiotec不变的坚持与承诺;Abbiotec将不断为满足客户的需要和让他们获得最好的成果而努力.

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